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pokój 326 
Zakład Chemii LekówDokonania naukowe
- Publikacje
Rational design of 5-HT<inf>6</inf>R ligands using a bioisosteric strategy: Synthesis, biological evaluation and molecular modelling
Autorzy: Staroń, J., Warszycki, D., Kalinowska-Tłus̈cik, J., Satała, G., Bojarski, A.J.
DOI: 10.1039/c5ra00054h
Date: 2015-01-01
Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity
Autorzy: Zagórska, A., Kolaczkowski, M., Bucki, A., Siwek, A., Kazek, G., Satala, G., Bojarski, A.J., Partyka, A., Wesolowska, A., Pawlowski, M.
DOI: 10.1016/j.ejmech.2015.04.046
Date: 2015-01-01
Fingerprint-based consensus virtual screening towards structurally new 5-HT<inf>6</inf>R ligands
Autorzy: Smusz, S., Kurczab, R., Satała, G., Bojarski, A.J.
DOI: 10.1016/j.bmcl.2015.03.049
Date: 2015-01-01
Rational Design, Pharmacomodulation, and Synthesis of Dual 5-Hydroxytryptamine 7 (5-HT<inf>7</inf>)/5-Hydroxytryptamine 2A (5-HT<inf>2A</inf>) Receptor Antagonists and Evaluation by [<sup>18</sup>F]-PET Imaging in a Primate Brain
Autorzy: Deau, E., Robin, E., Voinea, R., Percina, N., Satała, G., Finaru, A.-L., Chartier, A., Tamagnan, G., Alagille, D., Bojarski, A.J., Morisset-Lopez, S., Suzenet, F., Guillaumet, G.
DOI: 10.1021/acs.jmedchem.5b00874
Date: 2015-01-01
New Arylpiperazinylalkyl Derivatives of 8-Alkoxy-purine-2,6-dione and Dihydro[1,3]oxazolo[2,3-f]purinedione Targeting the Serotonin 5-HT<inf>1A</inf>/5-HT<inf>2A</inf>/5-HT<inf>7</inf>and Dopamine D<inf>2</inf>Receptors
Autorzy: Chłoń-Rzepa, G., Zagórska, A., Bucki, A., Kołaczkowski, M., Pawłowski, M., Satała, G., Bojarski, A.J., Partyka, A., Wesołowska, A., Pȩkala, E., Słoczyńska, K.
DOI: 10.1002/ardp.201500015
Date: 2015-01-01
Synthesis of Some Aminophosphonates Bearing N-(Fluorophenyl)-piperazynyl Moiety and Their Activity toward Serotonin Receptors
Autorzy: Lewkowski, J., Jóźwiak, A., Tokarz, P., Zagórski, P.M., Hamera, R., Cal, D., Satała, G., Bojarski, A.J.
DOI: 10.1002/hc.21259
Date: 2015-01-01
Arylsulfonamide derivatives of (aryloxy)ethylpiperidines as selective 5-HT<inf>7</inf>receptor antagonists and their psychotropic properties
Autorzy: Zajdel, P., Canale, V., Partyka, A., Marciniec, K., Kurczab, R., Satała, G., Siwek, A., Jastrzębska-Więsek, M., Wesołowska, A., Kos, T., Popik, P., Bojarski, A.J.
DOI: 10.1039/c5md00166h
Date: 2015-01-01
N-(4-Arylpiperazinoalkyl)acetamide derivatives of 1,3- and 3,7-dimethyl-1H-purine-2,6(3H,7H)-diones and their 5-HT<inf>6</inf>, 5-HT<inf>7</inf>, and D<inf>2</inf>receptors affinity
Autorzy: Zmudzki, P., Satała, G., Chłoń-Rzepa, G., Bojarski, A.J., Popik, P., Zajdel, P.
DOI: 10.1515/hc-2014-0200
Date: 2015-01-01
New 7-arylpiperazinylalkyl-8-morpholin-4-yl-purine-2,6-dione derivatives with anxiolytic activity - Synthesis, crystal structure and structure-activity study
Autorzy: Chłoń-Rzepa, G., Zmudzki, P., Pawłowski, M., Wesołowska, A., Satała, G., Bojarski, A.J., Jabłoński, M., Kalinowska-Tłuścik, J.
DOI: 10.1016/j.molstruc.2014.03.018
Date: 2014-01-01
New 1-arylindoles based serotonin 5-HT<inf>7</inf>antagonists. Synthesis and binding evaluation studies
Autorzy: Sagnes, C., Fournet, G., Satala, G., Bojarski, A.J., Joseph, B.
DOI: 10.1016/j.ejmech.2014.01.055
Date: 2014-01-01
